Therapeutic Drug Monitoring in Rheumatic Diseases
نویسندگان
چکیده
منابع مشابه
Therapeutic drug monitoring in rheumatic diseases: utile or futile?
Rapid and effective suppression of inflammation is a primary goal in the treatment of rheumatic diseases. However, the therapeutic effect of most medications may be slow to manifest, in the order of weeks or months in the case of DMARDs. Monitoring of drug concentrations allows the possibility of appropriate dose adjustment or changes in medication to achieve more rapid or better outcomes. We r...
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متن کاملTherapeutic drug monitoring
(Suggestions are based on Level III and IV evidence) • In both adults and children, C2 monitoring of CSA is superior to C0 as a predictor of AUC 0–4 and AUC 0–12. The C3 level is marginally superior to C2 for AUC 0–12. • Targeting AUC 0–4 levels for CSA of greater than 4400 ng/mL or C2 levels of greater than 1.5 by the end of the first week post transplant is associated with less acute rejectio...
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ژورنال
عنوان ژورنال: Hong Kong Bulletin on Rheumatic Diseases
سال: 2016
ISSN: 2415-153X
DOI: 10.1515/hkbrd-2016-0009